Scenario 2: A patient with ventilator-associated bacterial pneumonia--introduction to clinical trial design issues.
نویسنده
چکیده
A prototypical patient is presented to introduce important design issues for clinical trials of antibacterials in the treatment of ventilator-associated bacterial pneumonia.
منابع مشابه
عنوان: Impact of Care Program on Ventilator-Associated Pneumonia Incidence: A Clinical Trial
چکیده: Background: Ventilator-associated pneumonia (VAP) is one of the common problems in patients who are under mechanical ventilation and increases the hospitalization duration and treatment expenses. The current study was conducted to determine the impact of a care program on VAP. Methods: This clinical trial was performed on intubated patients who were under mechanical ventilation in Intens...
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Introduction: Ventilator-associated pneumonia (VAP) is one ofthe most popular nosocomial infections in the intensive care unitsand the nurse’s role in preventing it is very important. The aim ofthis study was to compare the effect of two methods of face to facetraining and work- shop clinical guidelines in prevention of VAP.Methods: In this experimental randomized clinical trial, theknowledge a...
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Introduction: The high prevalence of ventilator- associated pneumonia among hospital infections requires attention to standard preventive measures in the long run so that the contribution of the standardized and standardized programs to the reduction of the prevalence of this infection is carefully investigated. Therefore, the present study aims to determine The effect of continuous airway care...
متن کاملCost Drivers of a Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia Phase 3 Clinical Trial
Background Studies indicate that the prevalence of multidrug-resistant infections, including hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), has been rising. There are many challenges associated with these disease conditions and the ability to develop new treatments. Additionally, HABP/VABP clinical trials are very costly to conduct given their c...
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Acidic pH of stomach, which is a normal physiological barrier against bacterial overgrowth, would increase by stress ulcer prophylaxis initiation and may lead to bacterial colonization and play as a source for infection transmission to the respiratory system which results in ventilator related pneumonia in patients admitted to the Intensive Care Units (ICUs). Therefore, finding methods to ...
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ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 51 Suppl 1 شماره
صفحات -
تاریخ انتشار 2010